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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIN1 All Species: 38.18
Human Site: S72 Identified Species: 60
UniProt: Q13526 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13526 NP_006212.1 163 18243 S72 S Q S R R P S S W R Q E K I T
Chimpanzee Pan troglodytes XP_001161914 174 19574 S72 S Q S R R P S S W R Q E K I T
Rhesus Macaque Macaca mulatta XP_001099116 145 16071 V55 G Q G E P A R V R C S H L L V
Dog Lupus familis XP_542080 163 18285 S72 S Q S R R P S S W R Q E K I T
Cat Felis silvestris
Mouse Mus musculus Q9QUR7 165 18352 S74 S Q S R R P S S W R Q E K I T
Rat Rattus norvegicus NP_001100171 165 18314 S74 S Q S R R P S S W R Q E K I T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089028 159 17622 S68 N Q S R R P S S W R Q D N I T
Zebra Danio Brachydanio rerio NP_957042 159 17688 S68 S Q S R R P S S W R E E N I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54353 166 18358 S75 K G S R R P S S W R E A N I T
Honey Bee Apis mellifera XP_624205 162 18033 S71 S G S R R P S S W R E E N I T
Nematode Worm Caenorhab. elegans NP_494393 168 19158 K77 S D H I T R S K D D A I N I L
Sea Urchin Strong. purpuratus XP_788025 152 17114 W62 D S R R P A S W K D D R I T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL42 119 12996 P28 R K A S W K D P E G K I I L T
Baker's Yeast Sacchar. cerevisiae P22696 170 19386 R79 S R R P A S H R S E N I T I S
Red Bread Mold Neurospora crassa O60045 182 20596 S91 N Q S R R P S S W R E S E I T
Conservation
Percent
Protein Identity: 100 93.6 81.5 98.7 N.A. 95.1 95.7 N.A. N.A. N.A. 86.5 79.1 N.A. 56 65 57.1 55.2
Protein Similarity: 100 93.6 84 98.7 N.A. 96.9 96.9 N.A. N.A. N.A. 93.8 88.9 N.A. 65 74.8 67.2 70.5
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. N.A. N.A. 80 86.6 N.A. 66.6 80 20 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. N.A. N.A. 93.3 93.3 N.A. 73.3 86.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 33.1 44.1 50.5
Protein Similarity: N.A. N.A. N.A. 53.9 60.5 63.7
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 73.3
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 14 0 0 0 0 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 7 7 0 0 0 0 7 0 7 14 7 7 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 0 7 7 27 47 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 14 7 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 7 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 20 14 80 0 % I
% Lys: 7 7 0 0 0 7 0 7 7 0 7 0 34 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 7 14 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 14 0 0 0 0 0 0 0 0 0 7 0 34 0 0 % N
% Pro: 0 0 0 7 14 67 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 60 0 0 0 0 0 0 0 0 40 0 0 0 0 % Q
% Arg: 7 7 14 74 67 7 7 7 7 67 0 7 0 0 7 % R
% Ser: 60 7 67 7 0 7 80 67 7 0 7 7 0 0 7 % S
% Thr: 0 0 0 0 7 0 0 0 0 0 0 0 7 7 74 % T
% Val: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 7 0 0 7 67 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _